Van Andel Research Institute work turns to heart muscle regeneration
Dr. Stephan Jovinge mlive.com
Patrick Center February 6, 2014 | WGVU Seeking out the unique cells that make up the heart muscle and figuring out how to make them regenerate is a new mission for the Van Andel Research Institute.Chairman and CEO, David Van Andel, calls this “game-changing work.”
“Think about having a noninvasive heart procedure that no longer involves having to open someone up to do it and you can begin to hypothesis there are all sorts of applications that you can put against this.”
The man exploring the science is Dr. Stefan Jovinge who comes to Grand Rapids from Lund University in Sweden.Here, they’ve given him the nickname, Dr. J.His work could ultimately resolve a supply and demand issue. There are an overwhelming number of patients suffering from heart failure for a variety of reasons and the fix is a heart transplant. There aren’t enough of those to go around.
“What we are doing is investigating and exploring the possibilities for the heart to repair itself or to use cells that can be transplanted, grown and transplanted into the heart to make it regain function without transplanting a new heart.”
Doctor Jovinge explains the heart grows throughout our lives even as its function begins to decline later in life.
“But it goes on all through your life after the age of 75, 40 percent of your heart muscle cells have been formed postnatally, after your birth actually, so it’s a significant portion. But when you get a sudden loss of heart muscle cells it’s not enough to cover for that and that’s where we come in.”
Clinical and translational research will be conducted at Spectrum Health's Frederik Meijer Heart and Vascular Institute.
More WGVU News
Friday Hop candy delivers flavor without the hangover GRAND RAPIDS, Mich. December 19, 2014 | WGVU Today is National Hard Candy Day. The ingredients for making hard candy is basic; syrup, citric acid, food coloring and flavoring. And for kids young and old it’s the flavor that matters. WGVU discovered a one-of-a-kind candy taste earlier this year at the American Homebrewers Association Conference held at Grand Rapids’ DeVos Place. ListenDownload US Senate race in Michigan drew $56M in spending LANSING, Mich. December 19, 2014 | AP The race for U.S. Senate in Michigan drew more than $56 million in spending from the campaigns and outside supporters. Snyder signs bills to streamline some courts LANSING, Mich. December 19, 2014 | AP Gov. Rick Snyder has signed legislation designed to streamline the district court system in Michigan by creating more flexibility for magistrates. Snyder signs bill to expand nuisance abatement LANSING, Mich. December 19, 2014 | AP Gov. Rick Snyder has signed legislation to expand local governments' power to file nuisance complaints against homeowners and businesses suspected of illegal activity such human trafficking or gun crimes. Michigan Lottery sales reach record $2.6 billion LANSING, Mich. December 19, 2014 | AP Michigan Lottery ticket sales have reached a record $2.6 billion in the 2014 budget year. Tighter Internet sales tax collections are OK'd LANSING, Mich. December 19, 2014 | AP Amazon.com and other online stores will have to collect Michigan's sales tax on purchases under legislation headed to Gov. Rick Snyder. 168-year-old Grand Rapids house restored as treatment center GRAND RAPIDS, Mich. December 19, 2014 | AP A 168-year-old Grand Rapids mansion has been renovated for use as a private treatment center for women with alcohol and drug addictions. Cyberbullying legislation sent to Gov. Snyder LANSING, Mich. December 19, 2014 | AP Michigan school districts would have to include cyberbullying in their anti-bullying policies and report bullying data to the state under legislation going to Gov. Rick Snyder. Michigan voters to decide road funding tax hike LANSING, Mich. December 19, 2014 | AP A proposed tax hike aimed at improving Michigan's transportation infrastructure and schools is heading to voters. Authorities: Man arrested in 1990 beating death GRAND RAPIDS, Mich. December 19, 2014 | AP Authorities say a 56-year-old man has been arrested in the 1990 beating death of a 23-year-old in Grand Rapids. 11 charter authorizes remain at-risk of suspension LANSING, Mich. December 19, 2014 | AP The Michigan Department of Education has decided to keep the status of 11 of the state's charter school authorizers at-risk of possible suspension. Michigan gets $349,000 in cell 'cramming' deal LANSING, Mich. December 19, 2014 | AP Michigan Attorney General Bill Schuette says the state will receive $349,000 as part of a $90 million national settlement with cellphone company T-Mobile.